I.Overview
Ultrafiltration (UF) assumes the core tasks of concentration, purification, buffer replacement and removal of impurities in the separation of biological products, and is especially suitable for the fine treatment of large molecules of biologically active substances (e.g. proteins, vaccines, nucleic acids). UF system is the gold standard of biologics separation, and its irreplaceable core value in biopharmaceuticals lies in: activity preservation, precise separation, and compliance guarantee.

II.Key technology flow
Typical route for downstream purification of monoclonal antibody:
cell culture solution → centrifugation/microfiltration → Protein A chromatography → virus inactivation → **UF/DF (ultrafiltration dialysis)** → purified chromatography → preparation

Plasmid DNA purification process:
bacteriophage lysis → alkaline extraction → ultrafiltration (100 kDa) → affinity chromatography → **tangential flow ultrafiltration (TFF)** → sterile filtration

III.Core Performance Parameters

IV.Key Points for Equipment Selection

V.Core Application Scenarios
Monoclonal Antibodies
Recombinant Proteins
Viral Vectors
Nucleic Acid Drugs
Vaccines

VI.Here is a guideline for you to get a proper quotation
Tell us the raw water/source of water(tap water, well water, or sea water, etc)
Provide water analysis report(TDS , conductivity, or resistivity, etc)
Required production capacity( 5m³/H, 50m³/H,or 500m³/H, etc)
What's the pure water used for( industrial,Food and Beverage,or agriculture, etc )

                                                                                             Shenzhen Hongjie Water Technology Co., LTD 

Shenzhen Hongjie Water Technology Co., Ltd. is a high - tech enterprise specializing in water treatment and environmental protection, dedicated to providing customers with comprehensive engineering solutions in the fields of pure water preparation, wastewater treatment and waste gas treatment. Headquartered in Shenzhen, relying on the innovative resources and technological advantages of the Guangdong - Hong Kong - Macao Greater Bay Area, the company has been deeply engaged in the environmental protection industry, driving green development with technology and contributing to the harmonious win - win of ecology and economy.

Core Business Areas 

Pure Water Systems: Offering customized solutions for industrial ultrapure water, pharmaceutical purified water, and electronic-grade high-purity water, applied in industries such as electronics semiconductors, biopharmaceuticals, and food & beverages. The solutions ensure water quality safety and stability, meeting demanding production needs.

Wastewater Treatment: Providing treatment technologies for industrial wastewater (including difficult-to-treat wastewater), domestic sewage, and reclaimed water, using membrane separation, biochemical treatment, advanced oxidation, and other processes to achieve compliance with discharge standards and resource recovery.

Waste Gas Treatment: Designing efficient purification systems for pollutants such as VOCs (volatile organic compounds), acidic and alkaline gases, and dust, combining adsorption, catalytic combustion, and biological degradation technologies. These systems help enterprises comply with environmental regulations and achieve clean production.

Technological Advantages

The company takes innovation as the engine, gathers senior environmental protection engineers and scientific research team, has a number of independent intellectual property rights of patented technology, and we have established strategic cooperation with famous universities and environmental protection organizations at home and abroad.Through intelligent control system, modularized equipment integration and full life-cycle services, we provide energy-saving, efficient, stable and reliable environmental protection engineering services.

Through intelligent control system, modularized equipment integration and full life cycle service, we provide customers with energy-saving, efficient, stable and reliable environmental protection engineering services.

Project Experience

With years of industry expertise, Hongjie Water has completed hundreds of environmental engineering projects, serving clients across sectors including electronics manufacturing, chemicals, new energy, and municipal utilities. We have earned client trust through a “turnkey project” model, establishing a reputation for “technical expertise and efficient service.”

Certifications & Honors

The company is certified under ISO Quality Management Systems and has been awarded titles such as "National High-Tech Enterprise" and "Guangdong Provincial Environmental Protection Industry Backbone Enterprise." We actively participate in the formulation of industry standards, continuously leading technological innovation in environmental protection.

Development Concept

Upholding the mission of "Purifying Water Sources, Guarding Blue Skies" , Hongjie Water remains steadfastly committed to customer needs, driven by technological innovation, and focused on sustainable development. We provide smarter, greener environmental solutions for global clients, contributing to the building of a low-carbon future.